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Signs and symptoms may present during transfusion or in the hours/days post transfusion that may indicate a possible transfusion reaction. The following is a list of possible indicators:
- Fever greater than 1°C (2°F) above pre-transfusion baseline
- Chills
- Backache
- Shortness of breath
- Respiratory distress
- Rash, hives, or itching
- Nausea or vomiting
- Chest pain
- Abnormal pain of indeterminate origin
- Hemoglobinuria (red or dark colored urine)
When a transfusion reaction is suspected: (These actions are tailored to LifeShare Compatibility customers. Always follow local procedures for evaluation of suspected transfusion reactions)
- Stop the transfusion
- Notify the attending physician
- Collect and label post-transfusion samples from patient: [One 7-mL EDTA (purple or pink top) sample and a 10-mL clotted (plain red top) sample]
- Complete LifeShare Form L-49, Report of Transfusion Complication
- Notify LifeShare of suspected transfusion reaction
- Send the following to LifeShare:
- Completed Form L-49
- EDTA and Red top samples
- Blood component bag with all attached tubing and fluids
Laboratory investigation will include:
- Clerical check of component bag, label, paperwork, and patient sample
- Repeat of ABO testing on the posttransfusion sample
- Visual check of Pre- and posttransfusion sample to evaluate for evidence of hemolysis
- Direct antiglobulin test (DAT) on posttransfusion sample
- Additional testing based on initial findings
In the event Transfusion Related Acute Lung Injury (TRALI) or Transfusion Associated Circulatory Overload (TACO) is suspected, additional information may be requested. |
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LifeShare Donor Centers
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